Acceptance and Commitment Therapy (ACT) and Cognitive Behavioral Therapy (CBT) are two powerful modalities often employed in the treatment of depression. Both have robust empirical support but address psychological distress in slightly different ways. Integrating ACT with CBT can offer a comprehensive approach to depression, leveraging the strengths of both to support healing and growth. This article explores how ACT can complement CBT interventions for depression, enhancing therapeutic outcomes.